ISSN 1662-4009 (online)

ey0017.4-14 | New paradigms | ESPEYB17

4.14. Circulating IGF-1 independently predicts blood pressure in children with higher calcium-phosphorus product levels

S Xargay-Torrent , E Dorado-Ceballos , A Benavides-Boixader , E Lizarraga-Mollinedo , B Mas-Pares , M Montesinos-Costa , F De Zegher , L Ibanez , J Bassols , A Lopez-Bermejo

To read the full abstract: J Clin Endocrinol Metab. 2020 Jan 1;105(1):dgz101.The aim of this prospective longitudinal study of 521 healthy children (8.8 ± 0.1) was to evaluate the correlation of circulating IGF-I levels with metabolic and cardiovascular parameters and the potential interaction with the Calcium-Phosphorus product (Ca*P). 158 subjects were re-evaluated after a follow-up of 5 years. Baseline IGF-I and IGF-I/IGFBP-3 molar r...

ey0015.2-20 | Placental miRNAs dysregulation in maternal obesity may be involved in mediating growth-promoting effects in offspring of obese mothers | ESPEYB15

Placental miRNAs dysregulation in maternal obesity may be involved in mediating growth-promoting effects in offspring of obese mothers

G Carreras-Badosa , A Bonmatí , FJ Ortega , JM Mercader , M Guindo-Martínez , D Torrents , A Prats-Puig , JM Martinez-Calcerrada , F de Zegher , L Ibáñez , JM Fernandez-Real , A Lopez-Bermejo , J Bassols

To read the full abstract: J Clin Endocrinol Metab. 2017 Jul 1;102(7):2584-2594Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but probably include genetic, epigenetic alterations and changes in fetal nutrient supply. Placenta, and particularly amniotic fluid, is the in utero ...